Your next "best friend" is waiting for you at your local shelter.
Please contact the shelters and rescues below to adopt a homeless animal.
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| Adopt-A-Pet of York County |  1253 |
York | 29745 | (803) 684-5353 |
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| Adopt-A-Rabbit.org - Rabbit Sanctuary, Inc. | 80036 |
Simpsonville | 29680 | |||
| Aiken SPCA / Shelter | 401 Wire Rd. | Aiken | 29801 | (803) 648-6863 |
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| Anderson County Animal Shelter | 615 Hwy. 28 Bypass | Anderson | 29624 | (864) 260-4151 |
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| Anderson County Humane Society | 2262 |
Anderson | 29622 | (864) 225-9855 |
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| Animal Adoption League - MyNextPet.com | 2453 |
Rock Hill | 29732 | (803) 325-8282 |
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| Animal Allies | 1097 Asheville Hwy. | Spartanburg | 29303 | (864) 576-6971 |
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| Animal Outreach | 11251 |
Rock Hill | 29731 | (803) 385-4873 |
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| Animal Protection League of South Carolina | 5354 |
Columbia | 29250 | (803) 783-2119 |
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| Beaufort County Animal Shelter | 23 Shelter Church Rd. | Beaufort | 29906 | (843) 846-3904 |
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| Beaufort Humane Association | 4326 |
Beaufort | 29903 | (843) 525-1211 |
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| Berkeley County PAWS | 903 |
Goose Creek | 29445 | (893) 688-4414 |
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| Berkeley County SPCA | 431 St. James Ave., Suite F, Crowfield Village Center | Goose Creek | 29445 | (843) 797-0610 |
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| Carolina Basset Hound Rescue | 80082 |
Charleston | 29416 | (843) 766-8838 |
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| Cat Rescue, Inc. | 1156 Shoreham Rd. | Charleston | 29412 | (843) 762-0711 |
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| Cat Rescuers | 208 Lockwood Dr. | Lexington | 29072 | |||
| Charleston Animal Society - a JASPCA Center Location | 2455 Remount Rd. | North Charleston | 29406 | (843) 747-4849 |
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| Chester County Animal Shelter | 2714 Dawson Dr. | Chester | 29706 | (803) 385-6341 |
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| Cherokee County Animal Shelter | 300 Yale St. | Gaffney | 29340 | (864) 487-8529 |
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| Colleton County SPCA | 2204 |
Walterboro | 29488 | (843) 538-2273 |
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| Community Animal Shelter of Hampton County | 1442 |
Varnville | 29944 | (803) 943-7567 |
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| Concerned Citizens for Animals - Simpsonville | 1332 |
Simpsonville | 29681 | (864) 243-4222 |
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| Critter Connection | 1480 Boiling Springs Rd. | Spartanburg | 29303 | (864) 578-9226 |
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| Dachshund Rescue of North America, Inc. | 3208 Montcrest Rd. | Columbia | 29210 | (803) 354-9109 |
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| Darlington County Humane Society | Animal Control Ln., Darlington 29532 (shelter) | 503, Darlington, SC 29540 (mailing) |
(843) 398-4402 |
info[at]darlington humane.com |
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| Feline Refuge, Inc. | 404 |
Mt. Pleasant | 29450 | (803) 884-1874 |
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| Feral Friends | 1434 |
Goose Creek | 29445 | (843) 863-1192 |
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| Florence Area Humane Society | 1007 Stockade Dr. | Florence | 29501 | (843) 669-2921 |
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| Foothills Humane Society | 500 Five Forks Rd. | Liberty | 29657 | (864) 843-9693 |
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| Frances R. Willis SPCA | 1116 |
Summerville | 29484 | (843) 871-3820 |
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| Grand Strand Humane Society | 3241 10th Ave. N. | Myrtle Beach | 29577 | (843) 448-9151 |
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| Grateful Goldens Rescue of the Low Country | 1406 Waterlily Dr. | Mt. Pleasant | 29464 | (843) 810-0146 |
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| Greenville Humane Society | 328 Furman Hall Rd. | Greenville | 29609 | (864) 242-3626 |
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| Greenwood Citizens for Animals | 115 Possom Hollow Rd. | Greenwood | 29648 | |||
| Greyhound Lifesavers | 213 Meetze Ave. | Lexington | 29072 | (803) 957-3866 |
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| Hilton Head Humane Association | 21790, 10 Humane Way |
Hilton Head Island | 29926 | (843) 681-8686 |
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| Home Away From Home Rescue | 2405 Lakeview Dr. | Florence | 29505 | (843) 665-1615 |
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| Horry County Humane Society | 2101 Industrial Park Rd. | Conway | 29526 | (843) 915-5172 |
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| Humane Society / SPCA | 121 Humane Ln. | Columbia | 29209 | (803) 783-1276 |
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| Humane Society of Cherokee County | 2223 |
Gaffney | 29342 | (864) 487-4757 |
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| Humane Society of Greenwood | 242 |
Greenwood | 29648 | (864) 942-8558 |
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| Humane Society of Marlboro County | 3162 J. Brigman Rd. | Bennettsville | 29512 | (866) 479-1709 |
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| Humane Society of McCormick County, Inc. | 900 |
McCormick | 29835 | (864) 391-5414 |
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| Humane Society of North Myrtle Beach Inc. / Myrtle Beach Animal Shelter | 409 Bay St. | North Myrtle Beach | 29582 | (843) 249-4948 |
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| Jasper Animal Rescue Mission | 404 Carter's Mill Rd., 1179 |
Ridgeland | 29936 | (843) 726-7799 |
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| JCCARE - Japanese Chin Care and Rescue Effort | South Carolina and South East Georgia | (912) 495-0566 |
TinaChar[at] bellsouth.net |
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| John Ancrum SPCA | 3861 Leeds Ave. | Charleston | 29412 | (843) 747-4849 |
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| Kershaw County Humane Society | 886 |
Camden | 29020 | (803) 432-2743 |
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| Lancaster County Animal Control & Shelter - Lancaster County Litter Control | 1809 |
Lancaster | 29720 | (803) 286-8103 |
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| Laurens County Humane Society | 233 Brown Rd. | Laurens | 29360 | |||
| Lexington County Animal Control | 321 Ball Park Rd. | Lexington | 29072 | |||
| Low Country Golden Retriever Rescue | 31256 |
Charleston | 29417 | (843) 571-7177 |
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| Low Country House Rabbit Society | ||||||
| Low Country Pit Bull Rescue | 31364 |
Charleston | 29417 | (843) 834-4312 |
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| Lucky Dog Rescue | Gaffney | 29340 | (864) 804-0990 |
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| Marion County SPCA | 15 |
Mullins | 29574 | (843) 464-2454 |
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| Miracle Animal Rescue Spay & Neuter Clinic | 102 |
Tillman | 29943 | (843) 227-2537 |
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| Molly's Militia, Inc. | 6816 |
North Augusta | 29861 | |||
| Morningstar Animal Rescue & Referral | 1626 Bees Creek Rd. | Ridgeland | 29936 | (843) 717-3444 |
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| National Brittany Rescue and Adoption Network | (843) 438-8103 |
Horsesrunwld31 [at]aol.com |
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| Net Pets | 563 |
North Myrtle Beach | 29597 | (843) 249-5262 |
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| New Hope Pit Bull Rescue | serving the Charleston and Tri-County areas | Goose Creek | 29445 | (843) 814-2974 |
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| Newberry County Animal Care and Control | 11494 SC Hwy. 34 | Newberry | 29108 | (803) 321-2185 |
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| Noahs Ark Animal Sanctuary & People Against Cruelty | 805 3rd Ave. | Ridgeland | 29936 | (843) 726-7997 |
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| Noble Ones Bully Breed Rescue | 131 Surlington Dr. | Ladson | 29456 | (843) 771-3997 |
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| Oconee County Humane Society | 321 Camp Rd. | Walhalla | 29691 | (864) 638-8798 |
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| Orangeburg County Animal Shelter | 1000 |
Orangeburg | 29116 | (803) 534-0045 |
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| Our Lady of Mercy's Catnip Cottage | 105 Coney Ct. | Summerville | 29483 | (843) 729-3967 |
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| Palmetto Equine Awareness & Rescue League | 362 |
Sandy Spring | 29677 | (864) 269-2281 |
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| Pet Haven of South Carolina | 28 Scarlett St. | Greenville | 29607 | (864) 350-3735 |
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| Pet Helpers | 1430 Folly Rd. | Charleston | 29412 | (843) 795-1110 |
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| Pets, Inc. | 300 Orchard Dr. | West Columbia | 29171 | (803) 739-9333 |
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| Project Military Pets - Foster Project | 563 |
North Myrtle Beach | 29597 | (843) 249-5262 |
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| Project Pet | 1777 |
Columbia | 29202 | (803) 407-0991 |
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| Project Zero | 235 Beaver Dam Rd. | Gaffney | 29341 | |||
| Pug Lover Rescue | 37343 |
Rock Hill | 29732 | (803) 980-7729 |
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| Purr-Fect Kitty Rescue | 820 Sunny Slope Dr. | Cowpens | 29330 | (864) 494-5928 |
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| Recycled Pets | 10626 |
Rock Hill | 29731 | (803) 981-5087 |
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| Richardson Rescue | 1968 Garvin Rd. | York | 29745 | (803) 684-6865 |
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| Sacred Vision Animal Sanctuary | 5023 Dick Pond Rd. | Myrtle Beach | 29588 | (843) 215-7729 |
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| Save Our Strays | 715 |
Lexington | 29071 | |||
| Save the Strays Animal Rescue | 722 |
Bethune | 29009 | (843) 334-8459 |
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| Saving Gaffney Pets Rescue | 263, 300 Yale St. |
Gaffney | 29342 | (864) 303-7753 |
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| SCARE - South Carolina Awareness & Rescue of Equines | 312 Shetland Ln. | Lexington | 29073 | (803) 422-6585 |
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| South Carolina Awareness, Rescue and Education for Equines | 362 |
Sandy Spring | 29677 | (864) 287-9939 |
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| South Carolina Greyhound Adoption Program - SC GAP | 414D 3rd Ave. S. | Surfside Beach | 29575 | (843) 828-4357 |
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| Spartanburg Humane Society | 150 Dexter Rd. | Spartanburg | 29303 | (864) 583-4805 |
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| SPCA Humane Organization | 1140 S. Guignard Dr. | Sumter | 29150 | (803) 773-9292 |
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| SPCA Orangeburg | 2872 Saint Matthews Rd. NE | Orangeburg | 29115 | (803) 536-3918 |
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| St. Frances Humane Society | 125 Ridge Rd. | Georgetown | 29440 | (843) 546-0780 |
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| Tri-County Humane Society | 108 |
St. Matthews | 29135 | |||
| True Ethics for Animals Rescue Sanctuary - TEARS | 531 |
Beaufort | 29901 | (843) 643-1889 |
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| Union County Animal Control | 1657 Jonesville Hwy. | Union | 29379 | (864) 429-2808 |
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| Union County Humane Society | 101 |
Union | 29379 | (864) 427-1594 |
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| Walter Crowe Animal Shelter | 460 Fair St. | Camden | 29020 | (803) 425-6016 |
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| WARM - Waccamaw Animal Rescue Mission | 1764 |
Conway | 29528 | (843) 347-6583 |
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| York County Humane Society | 2036 Carolina Place Dr. | Fort Mill | 29708 | (803) 322-6495 |
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